Basic Information
VIS ID
TVIS10018404
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1784
Integrated sequence
TCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCT| |GTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGC
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37.55
Start
86799905/87504088 (Hg38)
End
86799905/87504088 (Hg38)
Nearest miRNA
hsa-mir-10397/Upstream/389134; hsa-mir-103a-1/Downstream/1162765;
Nearest TSS
ENST00000502646/Upstream/91069; ENST00000504287/Downstream/157954;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/91027, chr5-CpG: 30/Downstream/637190
Nearby gene
CCNH
Upstream sequence
ACCTGAGCAGCTCGACGACGTACACACTCATCAGCCAGTGCAGGAACTTGGCCAGGATCTCCTCACGCAGACGGTGCTCTGCGGCCGGAACACAGCCAAC
Downstream sequence
ATGAGTAGTGCACTGGAACTTTTAGTCACAGCTGCACTTCCAAATCACAGTATGTTACCTTACAGTGTTATAAGCAAAAACCAGCTGCAAGCAGAGAAAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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