hsa-mir-6780a-3p _LIHC.png
GRM8 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018406
Fusion event
HBV-GRM8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1795
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr7
Cytoband
q31.33
Reference genome
GRCh37.55
Start
126876033/127235979 (Hg38)
End
126876036/127235982 (Hg38)
Location type
Intron9
Target gene
GRM8
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-491-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-877-3p
Nearest miRNA
hsa-mir-10525/Upstream/177795; hsa-mir-10399/Downstream/845879;
Nearest TSS
ENST00000635602/Upstream/20852; ENST00000418215/Downstream/7237;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2305834, chr7-CpG: 237/Downstream/15264
Upstream sequence
TACTGTTTGTGCCTTAAGACTTCTCAGTATAAAGGGAGAATTGCTTCATAATCTTACACGGTTTAGTTCTATTCAAGTTGGTTAGACTATGGTGTTCATC
Downstream sequence
AAACCTTCCAAAATGAGAATGTGTTCATATATTTTGCTTATTTTACtttatttttgattgacaatttatatgtatttatggggcataatgtgatggttta
Target sequence
CTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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