Basic Information
VIS ID
TVIS10018408
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1795
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
GRCh37.55
Start
66846933/65087175 (Hg38)
End
66846933/65087175 (Hg38)
Fragile sites / regions
FRA10C
Nearest miRNA
hsa-mir-1265/Upstream/1714127; hsa-mir-107/Downstream/2316176;
Nearest TSS
ENST00000439456/Upstream/162657; ENST00000634479/Downstream/36492;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/32872, chr10-CpG: 39/Downstream/2676910
Nearby gene
LINC02671
Upstream sequence
CAGGTAAGTAATCAATTAAAAGAGGACCCTTCAATGATCAATTCTGATACTTGAAAAAGCTCAAGCTTAAACGTGTTTTTGCATTGAAAATGTGTCTGTG
Downstream sequence
AGTGCATCAACATCCATCTAGCAGAGAGAAAAGGGGCACTGAAGCAGCTATGTCTGCCAGGGGCTAGGGGCTCCCTTGCAGACAGCAATGCTACAATAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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