Basic Information
VIS ID
TVIS10018410
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1788
Integrated sequence
CGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAG| |GCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTG
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37.55
Start
103498077/103627349 (Hg38)
End
103498077/103627349 (Hg38)
Location type
Intronic
Target gene
LOC100190922 ; LOC105369463
Nearest miRNA
hsa-mir-10392/Upstream/2107444; hsa-let-7a-2/Downstream/222557;
Nearest TSS
ENST00000527297/Upstream/158960; ENST00000527804/Downstream/267922;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/535029, chr11-CpG: 43/Downstream/409328
Nearby gene
DYNC2H1
Upstream sequence
CACCTTATTCATGGCTGAAGTCACCTCTTGGTTACAGTAGCGTAGCGTGCCCGTGTGCATGTCCTTTGCGCCTGTGACCACCACCCCAACAAACCATCCA
Downstream sequence
aatcatgtggtttttgcctttagttccatttgatgaatcatatttattaatttgtatattttgaagcaatattacatcccagtgataagcctaattaatt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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