Fusion event
HBV-PDGFD integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
TTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCA
End
104007729/104137001 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/287021; hsa-let-7a-2/Downstream/7210756;
Upstream sequence
AGCTGAAGCATCAGAAGAAACAGATGAAAATGATTTGATCCTGGAAGTAACTGCAGGAGTTGGAGGTCAGGAGGCAATGTTGTTTACTTCAGAGATATTT
Downstream sequence
GATAGGTATCAGCAATATGCTGCATTTAAAAGATGACATTTTGAAACCCTGGAATATTTTCCAAGTGAAATAGGTGGCCGTAGACATGCGTCTGCCAGCA
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.