VISDB Viral Integration Site DataBase

VIS ID

TVIS10018413

Fusion event

HBV-PDE3A integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1767

Integrated sequence

TTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGT| |CTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTC

Chromosome

chr12

Cytoband

p12.2

Reference genome

Start

End

20795065/20642131 (Hg38)

Location type

Intron10

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-128-3p ; hsa-mir-211-5p ; hsa-mir-3680-3p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-3915 ; hsa-mir-1224-5p ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-3928-3p ; hsa-mir-5582-3p ; hsa-mir-8055 ; hsa-mir-129-5p ; hsa-mir-4776-3p ; hsa-mir-1304-5p ; hsa-mir-4677-5p ; hsa-mir-192-3p ; hsa-mir-2116-5p ; hsa-mir-22-5p ; hsa-mir-3613-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-8485 ; hsa-mir-7150 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-7843-3p ; hsa-mir-5585-5p ; hsa-mir-3191-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-942-5p ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-3128 ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-518c-5p ; hsa-mir-6814-5p ; hsa-mir-3614-3p ; hsa-mir-7849-3p ; hsa-mir-6818-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-377-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6846-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-3182 ; hsa-mir-3120-5p ; hsa-mir-1237-3p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-361-5p ; hsa-mir-3171 ; hsa-mir-2115-3p ; hsa-mir-1265 ; hsa-mir-5692a ; hsa-mir-106a-3p ; hsa-mir-6844 ; hsa-mir-4684-3p ; hsa-mir-103a-2-5p ; hsa-mir-8066 ; hsa-mir-1267 ; hsa-mir-3147 ; hsa-mir-367-5p ; hsa-mir-4328 ; hsa-mir-4425 ; hsa-mir-450a-1-3p ; hsa-mir-4652-3p ; hsa-mir-4747-5p ; hsa-mir-5196-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/2968737; hsa-let-7i/Downstream/3570290;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/89061, chr12-CpG: 34/Downstream/795404

Upstream sequence

aatctattttgttgctcaaattgtttcagcctctgtcattgagagctctttcaggttggttcccttgtccctttgatatgcccccatccttttgttttgt

Downstream sequence

AAAGATGTTTTATCCATGCCTAACGAGCAAGTGAGCATGAGTCCCAGTGGAAGTGAACATAAAGATTCCACAGCCCTCAAGAAAAACACTAAggctgggc