Fusion event
HBV-HP integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTT
End
72093086/72059187 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/2028690; hsa-mir-11401/Downstream/4809749;
Upstream sequence
AAGCCAGTAGGATTCAATCTGAAGTCAGGGATAACAGAGCCGGGGGCGGAGGCTAGGTCTCCTTACATATTTTGTTCACAATGGGACTAGAACACTCTGC
Downstream sequence
GGTGGGTGCTGAGCACTTAAGAGAGCAGGCAGGCGTCCAGCGGGGAACGTCCTAGAGGCACAGCCTTCCAGTGCGGCTTCCTCTGAGCACACAAGAGCCA
Target sequence
GGAGTGTACACCTTAAACAATGAGAAGCAGTGGATAAATAAGGCTGTTGGAGATAAACTTCCTGAATGTGAAGCA
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.