VISDB Viral Integration Site DataBase

VIS ID

TVIS10018415

Fusion event

HBV-ACADVL integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

651

End

885

Integrated sequence

GCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTA

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7128125/7224806 (Hg38)

Location type

Intron16

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-31-3p ; hsa-mir-615-3p

Nearest miRNA

hsa-mir-1253/Upstream/1014; hsa-mir-10226/Downstream/863250;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/3994, chr17-CpG: 75/Downstream/9233

Upstream sequence

TGAGATAGACTATATTATTGTCCCATATGTTCTCTGTACCTCTTTGtgggaggattacacctccctaccatgttgacatcaagcttagccatgtaactgt

Downstream sequence

AGGGCCTCAAGATCCCTGAGTGAGGGCCACCCCACGGCCCAGCATGAGAAAATGCTCTGTGACACCTGGTGTATCGAGGTGAGACTCGGGGCTGCCAAGC

Target sequence

GTAAGTGGCCAGGGGTCCAGGAGAGCCTGCATCAGGGACTGCAGCCGATGGCCCCTCTGAGCCCCGCACTGTCCCCATCTCTTAAGGCAGTACGGGCTCTGGAGCAGTTTGCCACTGTGGTGGAGGCCAAGCTGATAAAACACAAGAAGGGGATTGTCAGTAAGTGAGCTCTACACCATTCCGCCCCTCCCTTTCCTCTCCTTGAGACTAATGcccccacccccacccccaccccACCTACCGGACAGATGAACA