VISDB Viral Integration Site DataBase

VIS ID

TVIS10018416

Fusion event

HBV-TTR integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

358

End

2477

Integrated sequence

CTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCC

Chromosome

chr18

Cytoband

q12.1

Reference genome

Start

End

29175081/31595118 (Hg38)

Location type

Intron2

Target gene

miRNAs that regulate target gene

hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-1273f ; hsa-mir-4735-5p ; hsa-mir-6872-3p ; hsa-mir-6890-5p ; hsa-mir-590-3p ; hsa-mir-2355-5p ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6777-3p ; hsa-mir-6890-3p ; hsa-mir-512-5p ; hsa-mir-6869-5p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p

Nearest miRNA

hsa-mir-1-2/Upstream/1296158; hsa-mir-122/Downstream/3996619;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/96555, chr18-CpG: 145/Downstream/89591

Upstream sequence

TTTGTATTAAATCATCatttataatattaaatcatcatttataatattaaatatatatataaaGGAGATTAGAGTGTTGGGACTTTGCAAAAACAATCGC

Downstream sequence

GGAAAACCAGTGAGTCTGGAGAGCTGCATGGGCTCACAACTGAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAATCTTACTGGAA