Basic Information
VIS ID
TVIS10018419
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1820
Integrated sequence
TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37.55
Start
26408018/28828054 (Hg38)
End
26408030/28828066 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/2236519; hsa-mir-122/Downstream/1470844;
Nearest TSS
ENST00000575820/Upstream/42986; ENST00000584482/Downstream/533897;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/649843, chr18-CpG: 128/Downstream/2213457
Nearby gene
CDH2
Upstream sequence
ttataacatgtttatGTGTGTTAGTTGGTGGGGGTGTATTACTTTGCCATGCCATTTGTTTCCTCCATGCGTAACTTAATCCAGACTTTCACACCTTATA
Downstream sequence
ggctcagTGTTTGTGACATTTGAATTCACTAAGTGCACCACAGATGAATAGACAAGTCTGTTAAATTCTAAAATCTAAATTTTATCATAGTTACTTATTC
Target sequence
caaggaaattga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate