Basic Information
VIS ID
TVIS10018421
Fusion event
HBV-LOC105371657 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1756
Integrated sequence
TAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT| |AGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATG
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37.55
Start
189394051/189424921 (Hg38)
End
189394051/189424921 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LOC105371657
Nearest miRNA
hsa-mir-101-1/Upstream/8986531; hsa-mir-1182/Downstream/3291407;
Nearest TSS
ENST00000473358/Upstream/519233; ENST00000419614/Downstream/350544;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/2743972, chr1-CpG: 56/Downstream/3383581
Nearby gene
BRINP3
Upstream sequence
aaatctcatgatatttcaaatgttttcattattactgtatctgtatggcaatctgtaagcagtgacctgtgatgttactattgcaattgttttggggcac
Downstream sequence
agacaataagaggttcaatgctctggccaggtgacacCCCACACCCTCCAGCCCCAAACACACACACACATACCAGAGGTGGCCTCAGAGCACACACTTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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