Basic Information
VIS ID
TVIS10018422
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1790
Integrated sequence
ACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGC| |ATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGG
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37.55
Start
76132312/75905186 (Hg38)
End
76132316/75905190 (Hg38)
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/814272; hsa-mir-10b/Downstream/3744104;
Nearest TSS
ENST00000437798/Upstream/186066; ENST00000445178/Downstream/1080775;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/194173, chr2-CpG: 32/Downstream/3087876
Nearby gene
GCFC2
Upstream sequence
cttgagcacagcttttgtatcttccctccatccactctcacaggcttccctctgaagctctgtcaggagtgtgccaattttcttggtcccttggtggcag
Downstream sequence
tcacattttcttctttctccatgtgtctctctttgtctctctcataaagacattcatgatggtatttaaggcccacctagataatcgaagttaatctctc
Target sequence
gtga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate