Basic Information
VIS ID
TVIS10018427
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1822
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
GRCh37.55
Start
108274786/107658330 (Hg38)
End
108274786/107658330 (Hg38)
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/5225964; hsa-mir-10b/Downstream/1483160;
Nearest TSS
ENST00000437798/Upstream/115581; ENST00000419650/Downstream/95782;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/113874, chr2-CpG: 429/Downstream/168493
Nearby gene
GACAT1
Upstream sequence
CTCCTTTCTGTCAAGGTAATACCCATATTGATTGTTTCTGATAAAATACTATGGGGTATAGTTTAGCAGTGAAGCAAAGGTGTCCCTTACAAGGCAAATA
Downstream sequence
aactgaatcttcgatgcaacagtattgggaagtgttgtccctgggagacgagttagcaatgaggggataatcccacatgaatgggattagttgttactat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate