Basic Information
VIS ID
TVIS10018431
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1820
End
2067
Integrated sequence
ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCA
Host Sequence
Chromosome
chr5
Cytoband
q12.1
Reference genome
GRCh37.55
Start
60612012/61316185 (Hg38)
End
60612012/61316185 (Hg38)
Fragile sites / regions
FRA5H
Nearest miRNA
hsa-mir-10397/Upstream/1612482; hsa-mir-103a-1/Downstream/10853282;
Nearest TSS
ENST00000502646/Upstream/51256; ENST00000252744/Downstream/16088;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/153358, chr5-CpG: 341/Downstream/14493
Nearby gene
ZSWIM6
Upstream sequence
TAAAACTATATAGTGTGCTAACTggcatcaacaaaatggcagaatgggaattcttagtgcttgacccctcacagaaccatcaatctgaacaaccatccat
Downstream sequence
tagctgggattacgggcactcaccaccacactcggctattttctgcatttttagtagagacagggttttcaccaggttggccaggctggtcttgaactcc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate