Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018439
Fusion event
HBV-MITF integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
Start
End
69908737/69859586 (Hg38)
Location type
Intron1
Target gene
miRNAs that regulate target gene
hsa-mir-96-5p ; hsa-mir-182-5p ; hsa-mir-137 ; hsa-mir-155-5p ; hsa-mir-98-5p ; hsa-mir-218-5p ; hsa-mir-675-5p ; hsa-mir-101-3p ; hsa-mir-2113 ; hsa-mir-147b ; hsa-mir-210-3p ; hsa-mir-6828-5p ; hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-3679-3p ; hsa-mir-513a-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6830-5p ; hsa-mir-4762-5p ; hsa-mir-224-5p ; hsa-mir-551b-5p ; hsa-mir-548c-3p ; hsa-mir-216a-5p ; hsa-mir-340-5p
Nearest miRNA
hsa-let-7g/Upstream/810551; hsa-mir-12124/Downstream/1682384;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/119529, chr3-CpG: 50/Downstream/1205597
Nearest cancer related gene
MITF(OG, No orient, 0)
Upstream sequence
GGCAAATCCCAGCATTTGCATGAAGACAGTGAGTAGTGCTGACAAACACCAGGCAACAGCTAGGGCCGCTTCTGATCTTTGTTCTTTTTTTATGCCATAG
Downstream sequence
GAGGCCACTTCTACAGCTGAATTGCATGTTGCTTTAAAATATTATAATACCTTGACTCCTGCTTGGAAGAAGAAAGAAACTGATGTTGTAGATGAAGATG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.