Basic Information
VIS ID
TVIS10018443
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1785
Integrated sequence
CAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTG| |TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC
Host Sequence
Chromosome
chr7
Cytoband
p21.2
Reference genome
GRCh37.55
Start
16061232/16021607 (Hg38)
End
16061232/16021607 (Hg38)
Nearest miRNA
hsa-mir-339/Upstream/8954562; hsa-mir-10399/Downstream/2105613;
Nearest TSS
ENST00000635602/Upstream/179247; ENST00000582683/Downstream/188881;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2030019, chr7-CpG: 17/Downstream/377890
Nearby gene
CRPPA
Upstream sequence
TCGTAGACTAAAAGATATGCTTATTGTGGAAACTGCAGACATGCTTCAGGCTCCTCTCTTTACTGCTGAAGCTTTACTTCGAGCTCATGGTAATGAAAGA
Downstream sequence
TGTAGTCTTTTCTGAAAACAAATCTTTAGCAACAATGGGTATAAGAATTAACACAATATTGAAATGCTTTTTTCAATCCTTTTTCCCGTAATTTAACTCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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