VISDB Viral Integration Site DataBase

VIS ID

TVIS10018448

Fusion event

HBV-MAML2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1369

End

1688

Integrated sequence

GTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTG

Chromosome

chr11

Cytoband

q21

Reference genome

Start

End

95978408/96245244 (Hg38)

Location type

Intron4

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-218-5p ; hsa-mir-6868-3p ; hsa-mir-6715b-3p ; hsa-mir-3605-3p ; hsa-mir-205-5p

Nearest miRNA

hsa-mir-10392/Upstream/1778664; hsa-let-7a-2/Downstream/96194;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/321043, chr11-CpG: 75/Downstream/144128

Nearest cancer related gene

MAML2(OG, No orient, 0)

Upstream sequence

GGACATTTTCCACATCCACACCTTCTCTTCCTGCTTTGAGTATTTTAGAGGACTGTGCCTCGTAGTAAGAAAAAAATGAAACTCAGTTTCTTGAACCACA

Downstream sequence

TTTTGGAACATAAATTCTTTACATCAGGCTTTGTGCTAGAAATAGCTATTTGCAATGCTTTTTCCAGAATTTTTAATGAGTGTATCTCTAGTTTCTTTTA