Basic Information
VIS ID
TVIS10018454
Fusion event
HBV-LINC01569 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1671
End
1783
Integrated sequence
ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCT
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37.55
Start
4302244/4252243 (Hg38)
End
4302244/4252243 (Hg38)
Location type
Intron2
Target gene
LINC01569
Nearest miRNA
hsa-mir-1225/Upstream/766774; hsa-mir-11401/Downstream/419075;
Nearest TSS
ENST00000527434/Upstream/745; ENST00000262366/Downstream/1536;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/67517, chr16-CpG: 78/Downstream/1200
Upstream sequence
ttttcctcttccttttagttcttctCTTTAAATGCCTTCTCACTCTGCACGGGGTCTAGACTTGACTTCTCCTTTGGCTCACTTCTTGCCTTTTGTTTCA
Downstream sequence
gtaccaatgtcaattacctggcttctatgctaactgtagctatgcaagatgttaacactgagggatactgggtgaTCTCCCTATACATCTCTTTCTTTTa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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