CYP2F1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018457
Fusion event
HBV-CYP2F1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1637
End
1738
Integrated sequence
TATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37.55
Start
41626390/41120485 (Hg38)
End
41626390/41120485 (Hg38)
Location type
Exon4
Fragile sites / regions
FRA19A
Target gene
CYP2F1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10395/Upstream/750578; hsa-let-7e/Downstream/749142;
Nearest TSS
ENST00000633603/Upstream/6053; ENST00000534009/Downstream/4233;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/30250, chr19-CpG: 36/Downstream/4095
Upstream sequence
CAAAGAAGCATTTGTGGAGCACCTTCTGTGTGCCCCTAGGTACTAGATGCCTGGACGGGGTCAGAAGGACCCTGACCCACCTTGAACTTGTTCCACACAG
Downstream sequence
GAAAACTGAAGGTCAGGAATTTTTTTTAACAGGCTGGATGGCACGATCTTTTTTTTTTTTAACAGGCTGGATGgcagccttgacctcctgggcccaaacc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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