PROKR2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018458
Fusion event
HBV-PROKR2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1797
Integrated sequence
TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh37.55
Start
5290407/5309761 (Hg38)
End
5290407/5309761 (Hg38)
Location type
Intron1
Target gene
PROKR2
miRNAs that regulate target gene
hsa-mir-148b-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1392190; hsa-mir-1-1/Downstream/2061847;
Nearest TSS
ENST00000382410/Upstream/133659; ENST00000611223/Downstream/4608;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/7345, chr20-CpG: 133/Downstream/5859
Upstream sequence
TCTCTAGCTTTCAAGTGTCTGCTACTTAGTCCATCTGTTGTTCTATTATGTTGTGTTTGGCAAACAGATGCAGGAGAAGAACACTATTGCCTTTTCTGTT
Downstream sequence
TAGCTCTCTCTCAATCTGGTTCCACCATAAAAAGTATTTCAATAACCCATGCCAAAGGGAATTTCCACATTTCTCCTTATTCTGTTGTCAATTCTTAAAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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