Basic Information
VIS ID
TVIS10018466
Fusion event
HBV-chr15 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr15
Cytoband
q25.3
Reference genome
GRCh37.55
Start
87761379/87218148 (Hg38)
End
87761379/87218148 (Hg38)
Nearest miRNA
hsa-mir-10393/Upstream/1392418; hsa-mir-11181/Downstream/728058;
Nearest TSS
ENST00000557528/Upstream/176094; ENST00000560153/Downstream/358781;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/1377264, chr15-CpG: 36/Downstream/1037275
Nearby gene
LINC00052
Upstream sequence
AGGAGCAGAAAATGAAGTCTAATGGGAATTTAACTTGGAACCAAGTTTCCGTTCTATCATTCTATTTCATATTTTTTACCCTATGGTTGAGCCCCTGCTT
Downstream sequence
CCAAAGGATAATGACCCATGGAAAGCCTATGGACCACTTCCCCATTGGACCAAGTGCTCATCAGATTATCTACCCCAGCTCTTCACCTCAGGGTCCTGGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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