Basic Information
VIS ID
TVIS10018467
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1821
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37.55
Start
27427877/29847912 (Hg38)
End
27427881/29847916 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/3256377; hsa-mir-122/Downstream/450994;
Nearest TSS
ENST00000575820/Upstream/319609; ENST00000583089/Downstream/865359;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1669701, chr18-CpG: 128/Downstream/1193607
Nearby gene
MIR302F
Upstream sequence
GAAGATGGATTTTCCTTTCAAGATCAGATCTTGGGCCTCAGAGTCAGCCTCACTATAGAAAGCAAGGGCTAGTCTCAGCTTCCCACAGAAGACTTGGTTT
Downstream sequence
actggctgcaccttgaaaagttactgtagttattacttttggttgatttaccatttagactttctacttacgacaagaatagtttatacaccacagttac
Target sequence
ttgt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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