Basic Information
VIS ID
TVIS10018470
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1836
Integrated sequence
AGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGC| |CTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTA
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37.55
Start
102307416/101690954 (Hg38)
End
102307424/101690962 (Hg38)
Fragile sites / regions
FRA2S ; FRA2A
Nearest miRNA
hsa-mir-1285-2/Upstream/381420; hsa-mir-10b/Downstream/741327;
Nearest TSS
ENST00000437798/Upstream/211564; ENST00000427603/Downstream/5888;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/216286, chr2-CpG: 131/Downstream/6125
Nearby gene
MAP4K4
Upstream sequence
AGACCACACCACTGTCTGTGACACAGTGGCCATAGGGAGGAGGCTGGGGGTGAGGCTGCGGTTGGTAAACAGCTGCACGAACATCGGTGAAGGGGCCAGA
Downstream sequence
CCTAACAAAACCAGACAAACCTGACAATCATTAACATTCTCATCCAGCTTTGCCCAACTACTTCCTACAATCCCATCTAGATTTCCAAAGCTGGGGCTAT
Target sequence
CCCAAGCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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