Basic Information
VIS ID
TVIS10018474
Fusion event
HBV-LOC105379143 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1734
Integrated sequence
AAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTG| |GGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCT
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh37.55
Start
118378120/119042425 (Hg38)
End
118378121/119042426 (Hg38)
Location type
Intron2
Target gene
LOC105379143
Nearest miRNA
hsa-mir-10397/Upstream/67755; hsa-mir-103a-1/Downstream/112211;
Nearest TSS
ENST00000502646/Upstream/4653; ENST00000515335/Downstream/28435;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/53716, chr5-CpG: 77/Downstream/28623
Upstream sequence
gccatgctgatagtttaaattcatggccacagattttaaaaggtaccaaatactgcctggacattttggctcattttttccactcttcagaacttctctt
Downstream sequence
ataCTTTCAGTATTGTTACTACTGATGGGGATTAAAATGATTGAATCCACTAGTAACAACAAAAAAAATCTTGGAATTACTTTTCTTTAATACTAGTATC
Target sequence
t
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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