Basic Information
VIS ID
TVIS10018476
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1803
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |CGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh37.55
Start
69633498/71637357 (Hg38)
End
69633504/71637363 (Hg38)
Nearest miRNA
hsa-mir-10226/Upstream/2537701; hsa-mir-1250/Downstream/3111250;
Nearest TSS
ENST00000595228/Upstream/40881; ENST00000538693/Downstream/234387;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/1467778, chr17-CpG: 26/Downstream/478475
Nearby gene
ROCR
Upstream sequence
GTTGGACACACAAGCATCTGATGTATTGGTTGTAGATAAAGTTCTGTTTCTTAACCTGGTTGCATTTTACATATTTTTGAAAATTTTAATGAAGCAGAAG
Downstream sequence
CTGTCTGTATGCACAGCCTGATGGTACCCAGACTAGCAGAAAGTTAATCCATTAATCACACTCCCCAGATACTGTGGGGGACAACCCATCCTTGTTTCCC
Target sequence
GCTTTG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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