Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018478
Fusion event
HBV-TERT integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2447
Integrated sequence
TTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCA| |ATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCC
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
Start
End
1282742/1282627 (Hg38)
Location type
Intron13
Target gene
miRNAs that regulate target gene
hsa-mir-138-5p ; hsa-mir-498 ; hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-512-5p ; hsa-mir-1207-5p ; hsa-mir-1266-5p ; hsa-mir-1182 ; hsa-mir-181a-5p ; hsa-mir-6776-3p ; hsa-mir-197-3p ; hsa-mir-6740-3p ; hsa-mir-6760-3p ; hsa-mir-532-5p ; hsa-mir-3064-5p ; hsa-mir-422a ; hsa-mir-346 ; hsa-mir-1226-3p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-143-3p ; hsa-mir-3161 ; hsa-mir-3605-5p ; hsa-mir-3620-3p ; hsa-mir-3682-3p ; hsa-mir-4323 ; hsa-mir-4712-3p ; hsa-mir-4733-3p ; hsa-mir-4758-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-7112-3p
Nearest miRNA
hsa-mir-4635/Upstream/219648; hsa-mir-10397/Downstream/26683;
Nearest CpG islands
chr5-CpG: 37/Target, None/Upstream, None/Downstream
Nearest cancer related gene
TERT(OG, No orient, 0)
Upstream sequence
ttatcatacaaatctagaatgaggaatatcctacaatgcaattggcttaaacttttcaaaaatatcaatgttatgaaagaaaataaaagatgaaaggact
Downstream sequence
AAACGAGAAGGACATGCCACATCCAGATCACCGAGGGCCTGGTGACCTCACCCCGGACCTGCACCATCCGGACACCGCACATCCAGCTCACCAAGGGCCT
Target sequence
CCCTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.