VISDB Viral Integration Site DataBase

VIS ID

TVIS10018482

Fusion event

HBV-SRSF1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

590

Integrated sequence

GATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGG| |AAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCA

Chromosome

chr17

Cytoband

q22

Reference genome

Start

End

56081716/58004355 (Hg38)

Location type

Exon1

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-7-5p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-505-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-744-5p ; hsa-mir-193b-3p ; hsa-mir-423-3p ; hsa-mir-149-5p ; hsa-mir-335-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-607 ; hsa-mir-1305 ; hsa-mir-4709-3p ; hsa-mir-155-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-6823-3p ; hsa-mir-377-5p ; hsa-mir-2114-3p ; hsa-mir-7113-5p ; hsa-mir-4762-5p ; hsa-mir-6782-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-6715a-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6753-5p ; hsa-mir-377-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-4653-3p ; hsa-mir-4424 ; hsa-mir-622 ; hsa-mir-6514-5p ; hsa-mir-4802-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-338-5p ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3681-3p ; hsa-mir-552-5p ; hsa-mir-6792-5p ; hsa-mir-107 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1255b-2-3p ; hsa-mir-6776-3p ; hsa-mir-33a-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-508-3p ; hsa-mir-4724-5p ; hsa-mir-6734-3p ; hsa-mir-3667-3p ; hsa-mir-34c-3p ; hsa-mir-500a-5p ; hsa-mir-34b-3p ; hsa-mir-4668-3p ; hsa-mir-548c-3p ; hsa-mir-9-5p ; hsa-mir-1227-3p ; hsa-mir-25-5p ; hsa-mir-4252 ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-508-5p ; hsa-mir-550b-2-5p ; hsa-mir-6087 ; hsa-mir-658 ; hsa-mir-766-3p ; hsa-mir-5186

Nearest miRNA

hsa-mir-10226/Upstream/1113000; hsa-mir-1250/Downstream/326877;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/15665, chr17-CpG: 139/Downstream/2088

Nearest cancer related gene

SRSF1(OG, No orient, 0)

Upstream sequence

gggtgacagagcaagattccgtctcaaacaacaacaacaacaaatgcagattcctgggcccccacccatctgtctatgtgaatcagatctcagggactgg

Downstream sequence

ATTTAATTTGTAAATTAAAGTCTTTTAAACATATGAACCAATTATGAATATTAGTTTAAAGGGGAAGGTGAGACTTAAAAGTATTCCCAACTAGATTATC