Fusion event
HBV-APOA2 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCA
End
161192841/161223051 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/1322836; hsa-mir-1182/Downstream/4135;
Upstream sequence
CTTTTTTTTTCTTTTTTTGCTGTCCTTTTTACACCTTATTTTTATCTCTACACTCTTGCATTCCTCACCTCCTTCACTGCACCCTCCCTGTCCTTAAACA
Downstream sequence
TGCCcacacacacacacacacacacacacacacacacacacacTCTTTTCAGCTGGGTCCACAGCAGTGAATCCTGGCCTCCTGCCATACCTCTGCCAGT
Target sequence
ACTTGGCCTCGGCCTGAAGCTCTGGGCTCTTGACCTTCTCCATCAGGTCCTTGCCATAGTCAGTCACGGTCTGGAAGTACTGAGAAACCAGGCTCTCCACACATGGCTCCTTTGCCTGTCTCCGAACCAAAGCTCC
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.