VISDB Viral Integration Site DataBase

VIS ID

TVIS10018487

Fusion event

HBV-HSP90B1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

461

End

601

Integrated sequence

TATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTG

Chromosome

chr12

Cytoband

q23.3

Reference genome

Start

End

104341086/103947308 (Hg38)

Location type

Intron16

Target gene

miRNAs that regulate target gene

hsa-mir-15a-5p ; hsa-mir-192-5p ; hsa-mir-16-5p ; hsa-mir-223-3p ; hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-mir-1-3p ; hsa-mir-148a-3p ; hsa-mir-484 ; hsa-mir-128-3p ; hsa-mir-92a-3p ; hsa-mir-218-5p ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-25-5p ; hsa-mir-7160-5p ; hsa-mir-658 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-6125 ; hsa-mir-4459 ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-3919 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-3123 ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-302f ; hsa-mir-3915 ; hsa-mir-7154-5p ; hsa-mir-3928-3p ; hsa-mir-4272 ; hsa-mir-181b-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181a-5p ; hsa-mir-181c-5p ; hsa-mir-433-3p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-101-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-1909-3p ; hsa-mir-3154 ; hsa-mir-3175 ; hsa-mir-3179 ; hsa-mir-4278 ; hsa-mir-4434 ; hsa-mir-4450 ; hsa-mir-4516 ; hsa-mir-4716-3p ; hsa-mir-5703 ; hsa-mir-582-5p ; hsa-mir-6132 ; hsa-mir-6722-3p ; hsa-mir-6732-5p ; hsa-mir-6770-5p ; hsa-mir-6789-5p ; hsa-mir-6794-5p ; hsa-mir-6805-5p ; hsa-mir-6824-5p ; hsa-mir-6836-5p ; hsa-mir-6878-5p ; hsa-mir-377-5p ; hsa-mir-4468 ; hsa-mir-455-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6516-5p

Nearest miRNA

hsa-let-7i/Upstream/16753; hsa-mir-1178/Downstream/644325;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/16275, chr12-CpG: 50/Downstream/9417

Nearest cancer related gene

HSP90B1(TSG, No orient, 0)

Upstream sequence

CTAGCActgcattttctagtacaataaccactagccattaaagagaagttaatataaaaaattaatatttaagttaatatttaattaaattaccagcctg

Downstream sequence

tatgtggtttctggctcctgtgagtgatacctcttgctctgcttcagctctcagttggacttgactgaatcattccttctcttcttgcccccttatgcct