VISDB Viral Integration Site DataBase

VIS ID

TVIS10018493

Fusion event

HBV-NOA1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1633

Integrated sequence

CTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCAC| |CAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACT

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

57834683/56968517 (Hg38)

Location type

Intron4

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-30b-3p ; hsa-mir-1273e ; hsa-mir-4451 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6894-5p ; hsa-mir-4722-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-1827 ; hsa-mir-3192-5p ; hsa-mir-4649-3p ; hsa-mir-4459 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-1273f ; hsa-mir-4735-5p ; hsa-mir-6890-5p ; hsa-mir-590-3p ; hsa-mir-655-5p ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-4436b-5p ; hsa-mir-6821-3p ; hsa-mir-4312 ; hsa-mir-3653-5p ; hsa-mir-6790-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6878-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6778-3p ; hsa-mir-212-5p ; hsa-mir-548s ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-3675-3p ; hsa-mir-374c-3p ; hsa-mir-6771-3p ; hsa-mir-5582-3p ; hsa-mir-548c-3p ; hsa-mir-7156-3p ; hsa-mir-1184 ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-4733-5p ; hsa-mir-3155a ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418

Nearest miRNA

hsa-mir-12113/Upstream/4255767; hsa-mir-1243/Downstream/3954102;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/59078, chr4-CpG: 109/Downstream/7951

Upstream sequence

TTACATACTCATTTTGCAGTATATTGAGCTGGTCAAgtgcaagccccgagccttggcagcttccatgtgtaccctgcaaagccacagggtctgagctccc

Downstream sequence

GTGAAGCAAATGGCAGATTTTTAAGAAAATACTTTTATTGAAAATATGATATATTATGATTTACCCGTAAAATAAAAAGTGATGAAAAATATGCCAGACT

Target sequence

TCT