VISDB Viral Integration Site DataBase

VIS ID

TVIS10018494

Fusion event

HBV-NOA1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1902

Integrated sequence

GCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC| |ATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCG

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

57836907/56970741 (Hg38)

Location type

Intron4

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-30b-3p ; hsa-mir-1273e ; hsa-mir-4451 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6894-5p ; hsa-mir-4722-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-1827 ; hsa-mir-3192-5p ; hsa-mir-4649-3p ; hsa-mir-4459 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-1273f ; hsa-mir-4735-5p ; hsa-mir-6890-5p ; hsa-mir-590-3p ; hsa-mir-655-5p ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-4436b-5p ; hsa-mir-6821-3p ; hsa-mir-4312 ; hsa-mir-3653-5p ; hsa-mir-6790-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6878-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6778-3p ; hsa-mir-212-5p ; hsa-mir-548s ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-3675-3p ; hsa-mir-374c-3p ; hsa-mir-6771-3p ; hsa-mir-5582-3p ; hsa-mir-548c-3p ; hsa-mir-7156-3p ; hsa-mir-1184 ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-4733-5p ; hsa-mir-3155a ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418

Nearest miRNA

hsa-mir-12113/Upstream/4257994; hsa-mir-1243/Downstream/3951878;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/61305, chr4-CpG: 109/Downstream/5727

Upstream sequence

ATAAATTGTGCATTGTAATTATAAGTTGTAAATTCTACTACAAAGGTCAGCTATGGTTAGATTCAGTGAGTTTTACCTTAAAATATTGGCTTAAAACAAT

Downstream sequence

gtgaggcactgtgcacagccTGAGTCTTAATACTTTCATTTCACAACAGAGATCCTTGGTTCAGTCTGGGAAACCCTGGTTTAAGACATCAAATAAGTTT