ALDOB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018498
Fusion event
HBV-ALDOB integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
256
End
1729
Integrated sequence
CGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGG
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37.55
Start
104189763/101427481 (Hg38)
End
104189929/101427647 (Hg38)
Location type
Exon5
Target gene
ALDOB
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-378a-3p
Nearest miRNA
hsa-let-7a-1/Upstream/3198264; hsa-mir-12126/Downstream/5173281;
Nearest TSS
ENST00000422679/Upstream/28392; ENST00000424154/Downstream/2228;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/28235, chr9-CpG: 34/Downstream/21528
Upstream sequence
ATTTATTGAACTGTCTATTCAAACCAATCATAGTCATATATTTAATGAGTGAACATAGGATATCGTTGGAGAATACTATAACAATATGTCAGCTATTGTC
Downstream sequence
AGTCACAAAAGAGAGAAAGGCTTCTTTGTACCTTTGTACCTGATCCATGGGGCTTCTAATAAAGGGAAGGAGTTCTCCCTTTGCTTAGCTTTCAATCCAC
Target sequence
CTGCTGACAGATGCTGGCGTAGCGAGCCAGGGCGTTGGCGTTTTCCTGGATAGCGAGGCTGGATGGACACTGGTCGGCAATCCTCAGCACAGCACGCCACTTCCCAAAGTCAACACCATCTTTCTTGTACTGAGCACAGCGCTCTGAGAGGCCATCAAGCCCTGCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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