AMBP _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018500
Fusion event
HBV-AMBP integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
429
End
1084
Integrated sequence
ATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTA
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
GRCh37.55
Start
116823872/114061592 (Hg38)
End
116823872/114061592 (Hg38)
Location type
Intron3
Fragile sites / regions
FRA9E
Target gene
AMBP
Nearest miRNA
hsa-let-7a-1/Upstream/2129423; hsa-mir-12126/Downstream/147842;
Nearest TSS
ENST00000422679/Upstream/33671; ENST00000451716/Downstream/13377;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/11483, chr9-CpG: 104/Downstream/36448
Upstream sequence
GTTTTACAATATTCTCTTAAGCAACATTTAAGAATAAATTTTCAATTAAATCTTTTCACCACAATAATGGTTTAAATAACATTTGTTTTGGTGAAAAAAA
Downstream sequence
CAGACCCCTGGCTCTGGGCTGCCCACTTCTGCAGTGAGGCCTGAATGCCCACGCAGGTCAGGGGAGGCCACTCTGCGATTCTCTTCCAGGGCCTTCCTTG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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