VISDB Viral Integration Site DataBase

VIS ID

TVIS10018501

Fusion event

HBV-SHLD2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1455

End

1730

Integrated sequence

ACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTT

Chromosome

chr10

Cytoband

q23.2

Reference genome

Start

End

88940883/87181126 (Hg38)

Location type

Intron7

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-187-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-133a-5p ; hsa-mir-586 ; hsa-mir-548v ; hsa-mir-4490 ; hsa-mir-4666a-5p ; hsa-mir-5700 ; hsa-mir-5089-3p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-4773 ; hsa-mir-222-5p ; hsa-mir-3925-5p ; hsa-mir-545-5p ; hsa-mir-802

Nearest miRNA

hsa-mir-1265/Upstream/916338; hsa-mir-107/Downstream/322755;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/85385, chr10-CpG: 27/Downstream/41810

Upstream sequence

ttggacaattttcaaaGACGGACTGATTCTCTGTCCAGTTGCCTCAGCTCAGGGGTTTGGGAGccctgctgatcttgcccctctggtggcggtaagcacc

Downstream sequence

TCAGATGAAAATGAGTCGAGCCCGGTGGAAGATTTACAGGGATTTGGGACCAGGGAGACAATGGAGTTTTAAATGTTGATAGCGTTTCACACCAAACACA