DLG2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018502
Fusion event
HBV-DLG2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
635
End
1739
Integrated sequence
ATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTC
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37.55
Start
85195010/85483966 (Hg38)
End
85195230/85484186 (Hg38)
Location type
Intron25
Target gene
DLG2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10392/Upstream/3593130; hsa-let-7a-2/Downstream/794147;
Nearest TSS
ENST00000527297/Upstream/350843; ENST00000530901/Downstream/40836;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2197473, chr11-CpG: 24/Downstream/144113
Upstream sequence
tccctcttgagtgtgtactttggatttgcaataaaagctccttgcctttcgcttcacctgacttgtctctaaattctttcttgtgatggtgtcaataacc
Downstream sequence
gatctttcccgccccccgttcctcccgacccctccacccgccctccctctcccaccgcccctcctcctcctccctaggcattaccattcaggacataggc
Target sequence
Ggcccgggtcttccaggagtcgggttgcttgggaatgcagcccaaagcgggtggtaaactccatttaaggctaaataccggcacgagaccgatagtcaacaagtaccgtaagggaaagttgaaaagaactttgaagagagagtacaagagggcgtgaaaccgttaagaggtaaatgggtcaggtccgcgcagtccgcccggaggattcaacccggtggcg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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