HSD17B6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018503
Fusion event
HBV-HSD17B6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37.55
Start
57171553/56777769 (Hg38)
End
57171556/56777772 (Hg38)
Location type
Intron2
Target gene
HSD17B6
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/2440455; hsa-let-7i/Downstream/416732;
Nearest TSS
ENST00000382841/Upstream/14445; ENST00000556875/Downstream/7167;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/25220, chr12-CpG: 79/Downstream/228312
Upstream sequence
TCAATTTATTACACATTGCCTGAGACTACTATAGAATGAAAATGTCTCATAAGATGTAGACCAGTAAGTCACTATTCTCTCATGGAAATCTCTTTATTCA
Downstream sequence
gcactttgggaggccggggtgggaggattgcttgagcccaggagttcaacaccagcctgggcaacacagtgagataccatctcaatttaaaaaaataata
Target sequence
cca
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate