Basic Information
VIS ID
TVIS10018504
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37.55
Start
68036021/67642241 (Hg38)
End
68036021/67642241 (Hg38)
Nearest miRNA
hsa-let-7i/Upstream/1391084; hsa-mir-1178/Downstream/1630916;
Nearest TSS
ENST00000382841/Upstream/52254; ENST00000537632/Downstream/6097;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/371974, chr12-CpG: 181/Downstream/6145
Nearby gene
DYRK2
Upstream sequence
gaaaatggctggttcctgccttaactgatgacattccaccattgtgatttgttcctgccccaccttaactgagtgattaaccttgtgaaattcctttcct
Downstream sequence
gggtactttcttactttctagtgctacaagatgctctagatcatctattttccctgccccaaacccagaatcagccagttctccaaaaaatggagaaacg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate