Basic Information
VIS ID
TVIS10018507
Fusion event
HBV-PKD1P6-NPIPP1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1414
Integrated sequence
GAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGG| |GACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGA
Host Sequence
Chromosome
chr16
Cytoband
p13.11
Reference genome
GRCh37.55
Start
15217035/15123178 (Hg38)
End
15217035/15123178 (Hg38)
Location type
Intron
Fragile sites / regions
FRA16A
Target gene
PKD1P6-NPIPP1
Nearest miRNA
hsa-mir-1225/Upstream/112781; hsa-mir-11401/Downstream/10897;
Nearest TSS
ENST00000527434/Upstream/28861; ENST00000552015/Downstream/31725;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/28706, chr16-CpG: 43/Downstream/4533
Upstream sequence
TTCCAGAGAGGACCTGGCCTTGGGAGGAGCGTGGGGGACTGAGATGGGGGAGGGGTCATTGGGATGATGCGGGCGCTACTTGGAATGTCCATTGTGAGGC
Downstream sequence
TGCCTCACAATGGACATTCCAAGTAGCGCCCGCATCATCCCAATGACCCCTCCCCCATCTCAGTCCCCCACGCTCCTCCCAAGACCAGGTCCTCTCTGGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate