Basic Information
VIS ID
TVIS10018508
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1822
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37.55
Start
26781384/28454366 (Hg38)
End
26781384/28454366 (Hg38)
Nearest miRNA
hsa-mir-1180/Upstream/93632; hsa-mir-10226/Downstream/407003;
Nearest TSS
ENST00000595228/Upstream/47169; ENST00000545060/Downstream/18927;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/47988, chr17-CpG: 55/Downstream/97901
Nearby gene
SLC13A2
Upstream sequence
ACCAGTCATTCTCCCTCTTCCTCTCAGGCGGGCAGGGCTGGGCAGCGGCCTGAGTCTCAGCGGACTTGTCCACCCGGAGTTGAGTCGGAGTGGCGAGCTG
Downstream sequence
agggttttagaagttgtgggccaggaaacagggacaaaaccaaatatatatttcacaatatcacaAACAGGAAATTCTCTTCctctcttcttgaactggg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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