VISDB Viral Integration Site DataBase

VIS ID

TVIS10018509

Fusion event

HBV-CALR integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

480

End

639

Integrated sequence

CTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCC

Chromosome

chr19

Cytoband

p13.13

Reference genome

Start

End

13054443/12943629 (Hg38)

Location type

Exon8

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-122-5p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-423-3p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-148a-5p ; hsa-mir-516a-5p ; hsa-mir-875-3p ; hsa-mir-1254 ; hsa-mir-3116 ; hsa-mir-3148 ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-6849-3p ; hsa-mir-6782-5p ; hsa-mir-412-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-6878-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-1225-3p ; hsa-mir-1253 ; hsa-mir-3179 ; hsa-mir-203a-3p ; hsa-mir-5681a ; hsa-mir-6742-3p ; hsa-mir-637 ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-1910-5p ; hsa-mir-6838-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-5197-3p ; hsa-mir-1252-3p ; hsa-mir-4533 ; hsa-mir-4518 ; hsa-mir-4468 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-1245b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-2278 ; hsa-mir-4428 ; hsa-mir-665 ; hsa-mir-216a-5p ; hsa-mir-4534 ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-7847-3p ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-3175 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-8085 ; hsa-mir-6787-5p ; hsa-mir-6731-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-5192 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-4693-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-6732-5p ; hsa-mir-6783-5p ; hsa-mir-4779 ; hsa-mir-3141 ; hsa-mir-6124 ; hsa-mir-342-3p ; hsa-mir-6716-3p ; hsa-mir-6771-3p

Nearest miRNA

hsa-mir-10395/Upstream/2993; hsa-let-7e/Downstream/892658;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/4538, chr19-CpG: 69/Downstream/2015

Upstream sequence

CAAAGAAGCATTTGTGGAGCACCTTCTGTGTGCCCCTAGGTACTAGATGCCTGGACGGGGTCAGAAGGACCCTGACCCACCTTGAACTTGTTCCACACAG

Downstream sequence

GTGAGGCCTGGTCCTGGTCCTGATGTCGGGGGCGGGCAGGGCTGGCAGGGGGCAAGGCCCTGAGGTGTGTGCTCTGCCTGCAGGCAGCAGAGAAACAAAT

Target sequence

CAGGTCAAGTCTGGCACCATCTTTGACAACTTCCTCATCACCAACGATGAGGCATACGCTGAGGAGTTTGGCAACGAGACGTGGGGCGTAACAAAG