VISDB Viral Integration Site DataBase

VIS ID

TVIS10018511

Fusion event

HBV-ELFN2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1008

End

1867

Integrated sequence

TTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGC

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

37751589/37355549 (Hg38)

Location type

Intron2

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1200 ; hsa-mir-1207-5p ; hsa-mir-1225-3p ; hsa-mir-1226-5p ; hsa-mir-1249-5p ; hsa-mir-1250-5p ; hsa-mir-1321 ; hsa-mir-134-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1909-3p ; hsa-mir-1910-3p ; hsa-mir-214-3p ; hsa-mir-3064-3p ; hsa-mir-3118 ; hsa-mir-3126-5p ; hsa-mir-3136-5p ; hsa-mir-3141 ; hsa-mir-3151-3p ; hsa-mir-3164 ; hsa-mir-3202 ; hsa-mir-3619-5p ; hsa-mir-3653-5p ; hsa-mir-3915 ; hsa-mir-3928-3p ; hsa-mir-4252 ; hsa-mir-4261 ; hsa-mir-4291 ; hsa-mir-4300 ; hsa-mir-4302 ; hsa-mir-4317 ; hsa-mir-4324 ; hsa-mir-4419a ; hsa-mir-4439 ; hsa-mir-4476 ; hsa-mir-4510 ; hsa-mir-4513 ; hsa-mir-4519 ; hsa-mir-4688 ; hsa-mir-4715-3p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4746-3p ; hsa-mir-4747-5p ; hsa-mir-4756-5p ; hsa-mir-4763-3p ; hsa-mir-486-3p ; hsa-mir-494-3p ; hsa-mir-512-5p ; hsa-mir-5196-5p ; hsa-mir-544b ; hsa-mir-558 ; hsa-mir-5591-5p ; hsa-mir-595 ; hsa-mir-6087 ; hsa-mir-6090 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-615-5p ; hsa-mir-636 ; hsa-mir-644a ; hsa-mir-6499-3p ; hsa-mir-6511a-5p ; hsa-mir-663b ; hsa-mir-6721-5p ; hsa-mir-6722-3p ; hsa-mir-6726-5p ; hsa-mir-6731-5p ; hsa-mir-6734-5p ; hsa-mir-6743-5p ; hsa-mir-6755-5p ; hsa-mir-6760-5p ; hsa-mir-6783-5p ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6820-3p ; hsa-mir-6824-5p ; hsa-mir-6827-5p ; hsa-mir-6834-5p ; hsa-mir-6855-3p ; hsa-mir-6857-3p ; hsa-mir-6871-5p ; hsa-mir-6875-5p ; hsa-mir-6876-5p ; hsa-mir-6883-5p ; hsa-mir-7108-5p ; hsa-mir-7112-5p ; hsa-mir-7515 ; hsa-mir-761 ; hsa-mir-8085 ; hsa-mir-920 ; hsa-mir-922 ; hsa-mir-9500 ; hsa-mir-4691-5p ; hsa-mir-6792-3p

Nearest miRNA

hsa-mir-1286/Upstream/1068597; hsa-let-7a-3/Downstream/488723;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/20195, chr22-CpG: 163/Downstream/17581

Upstream sequence

agcccacacctgacctgtcactggcagagggTGCGCTCGCCCTGAGACCCATCAGGAGCACCTGCCGTGGTGGCGAGGTGGAGGTGGTGCTGGCGTCCTA

Downstream sequence

gcggggccatccctgagcacccATCGATTGTGGCCTTGTCTCCCCACCCAAAGGGCTCCCTTCCCAAGTGTTGCCAGGAGCCCCAGCAGACATCTTCTAC

Target sequence

Ggcttcctctcattgtcaagtcccttctcagacctcacctctgca