Basic Information
VIS ID
TVIS10018512
Fusion event
HBV-SLFNL1-AS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37.55
Start
41492784/41027112 (Hg38)
End
41492784/41027112 (Hg38)
Location type
Intron1
Target gene
SLFNL1-AS1
Nearest miRNA
hsa-mir-12136/Upstream/269740; hsa-mir-101-1/Downstream/2144540;
Nearest TSS
ENST00000473358/Upstream/3875; ENST00000422305/Downstream/10340;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9091, chr1-CpG: 155/Downstream/214173
Upstream sequence
tacagcatgatgctgaggtttggggtagagatcctgtcatccagagagtgagcataggacccaataagtggcttattaacccacacttccctcctagcct
Downstream sequence
GAAGGGACTGGAGTGAGTGTGGGAGGAAAATGGAGGGAcagaagggcaaggcagccttgcagagacattaagaacttggatagccagatcttggttccta
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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