Basic Information
VIS ID
TVIS10018514
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
458
Integrated sequence
CTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCA| |AGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTAT
Host Sequence
Chromosome
chr1
Cytoband
q24.1
Reference genome
GRCh37.55
Start
166245822/166276585 (Hg38)
End
166245822/166276585 (Hg38)
Location type
Intronic
Target gene
LOC112268276 ; LOC284685
Nearest miRNA
hsa-mir-101-1/Upstream/121787; hsa-mir-1182/Downstream/1722075;
Nearest TSS
ENST00000473358/Upstream/109616; ENST00000425271/Downstream/58299;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/109374, chr1-CpG: 112/Downstream/562519
Nearby gene
MIR921
Upstream sequence
ATGCTAGAATTCTTGTACTGTTCTAAGTTTGTTATTATGTCTCATGTGGAAGTCAGAATGTCCTGGAGACTGACTCCTGGTTTGGCTTTGATATAAGCAC
Downstream sequence
catgaaccatggccaaataagatggcaaatttgatctaccaatgtcatgggctttgttattgttttagagacagggtctcattctgtcaccggggttgct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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