Basic Information
VIS ID
TVIS10018515
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1804
Integrated sequence
ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC| |GCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT
Host Sequence
Chromosome
chr1
Cytoband
q42.3
Reference genome
GRCh37.55
Start
234757358/234621612 (Hg38)
End
234757358/234621612 (Hg38)
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/315073; hsa-mir-1537/Downstream/568422;
Nearest TSS
ENST00000473358/Upstream/12087; ENST00000429269/Downstream/7699;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/10334, chr1-CpG: 30/Downstream/482627
Nearby gene
LINC00184
Upstream sequence
TTTCCTGTTTTCCCAATGTCTGCAATTCTAGTACATTTGAAGATCTTAATTCAGATGTATATACTATTTAATATTGCTTGTAAAGTTTAGTATTTCAAGA
Downstream sequence
TCTTCCTCTGCACCCTGCTGCGGCCCCCACCCACCCACCACAAACCCTGCCACAGAGCCCCAATGATGGCGATTGCCCCTTCTAATTGCAGCCACACTCC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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