ITGA6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018516
Fusion event
HBV-ITGA6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37.55
Start
173317053/172452325 (Hg38)
End
173317053/172452325 (Hg38)
Location type
Intron1
Fragile sites / regions
FRA2G
Target gene
ITGA6
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-32-5p ; hsa-mir-30a-5p ; hsa-mir-15b-5p ; hsa-mir-92b-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-140-3p
Nearest miRNA
hsa-mir-128-1/Upstream/3869307; hsa-mir-10b/Downstream/2715308;
Nearest TSS
ENST00000437798/Upstream/23722; ENST00000497107/Downstream/13687;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/23870, chr2-CpG: 143/Downstream/103147
Upstream sequence
TTTGACAAATGCCCTGAGAGTCTATCCTGGTGCACCCTGGAGCAAGCCTGGTGGTTCAGACCACAGGTCTGTGCAACGTTTTGTGTTTTCCCATCCTCCA
Downstream sequence
CAGGGACTGGTGGGAGTCAGTGGCAGCAAGTCTTGTCTAAAGGTGTGAGCAGCAACAAAGCAACACACGAGGCAGGAAAGGACTAGGCTTCATTAATGGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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