Basic Information
VIS ID
TVIS10018517
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1756
Integrated sequence
TAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT| |AGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATG
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37.55
Start
186329102/185464375 (Hg38)
End
186329102/185464375 (Hg38)
Nearest miRNA
hsa-mir-10b/Upstream/1085331; hsa-mir-1244-1/Downstream/2833117;
Nearest TSS
ENST00000437798/Upstream/598010; ENST00000465275/Downstream/274346;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/865513, chr2-CpG: 53/Downstream/274290
Nearby gene
FSIP2-AS2
Upstream sequence
GGCCATAGCAGTAGCACTGGTATCTGACACCATGCACATACTTCTCCCATGAATCTCCAATTTGATAAAACGTCCCAGTCTCTGAATCCTGGCATTGGTC
Downstream sequence
cacagtatgctgtcagaccacagtagaattcaaatagaaatcaataacagaactagagctgaaaaatccccaatatgtggagattaaacaaaataattaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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