Fusion event
HBV-RTP2 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAG
End
187416444/187698656 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/911628; hsa-mir-28/Downstream/990125;
Upstream sequence
GTGGAGGTTTGGCTTAGAGCAGGAACACGAGGCTCCCGTTTGGGGAACAAGGAGCCTCAGGAGGCCCTTTCAGCACTAGACAGGCCAGAGATGCTGAAAA
Downstream sequence
CTCCAGCAGCTTCTCGCTGGGCTTCCAGTGAACGATGCCCTCCTGGCAGGCCTCACAGAACTCTGCACGATGCGGCCCGCTGTCCGGGCGGCTGGCCACG
Target sequence
gtcatatgttgaatctgtagcaggatcaagtccagactgtgtcctccccactctcaagcccatgtgccctctcCCACCCTTAACCAGCTCCACTAAAAGAAGGCAGGACTGAGGAAGGAGAACTGCAGGTAAACAACGAGCAGGCAGAGAGAGGCCCAGAAGAGGCACCAGCGAAGAGACAAGAAGTTGTAGCCGGATCCCGCCTGGGCCCTCGGCTTGGAGGCTTCAGAGGTGTAGGTGGTCACCTCCTC
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.