Basic Information
VIS ID
TVIS10018531
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1817
Integrated sequence
TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
GRCh37.55
Start
46712940/46745203 (Hg38)
End
46712956/46745219 (Hg38)
Nearest miRNA
hsa-mir-10398/Upstream/1547433; hsa-mir-10524/Downstream/5399130;
Nearest TSS
ENST00000381078/Upstream/9510; ENST00000445060/Downstream/1698;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/9624, chr6-CpG: 123/Downstream/563500
Nearby gene
ANKRD66
Upstream sequence
CCCATGGAAAACCGTAAGGATGAGAATCCGGTCTCATACCGTCAGGCAGTGCTGCCACAACCCTGCGTCGCAACTCCAGGATCAGCCCCAAGCACGGCTG
Downstream sequence
acgcttcatttatactgtccttcccttacccaaacctggccctaccctagtcacctcctaccacgaatgtgagcaccttccaccaggttcgtcaagccag
Target sequence
aacacattgaaacaga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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