CLVS1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018536
Fusion event
HBV-CLVS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr8
Cytoband
q12.3
Reference genome
GRCh37.55
Start
62398573/61486014 (Hg38)
End
62398573/61486014 (Hg38)
Location type
Intron5
Target gene
CLVS1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-124-1/Upstream/18589739; hsa-mir-10400/Downstream/228774;
Nearest TSS
ENST00000518652/Upstream/21443; ENST00000523042/Downstream/40072;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/346142, chr8-CpG: 102/Downstream/227983
Upstream sequence
tgcacttgactggcgggagagacctctgctggggctgcacttactaagcatgtagctaggacacaaatatctccacatttgggctcatttagagacgtct
Downstream sequence
gctgcataccaacatggcacatgtatacatatgtaactaacctgcacgttgtgcacatgtaccctacaacttaaagtataattaaaataaataaataaat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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