Basic Information
VIS ID
TVIS10018537
Fusion event
HBV-LOC105375631 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1814
Integrated sequence
GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37.55
Start
90048798/89036569 (Hg38)
End
90048798/89036569 (Hg38)
Location type
Intronic
Target gene
LOC105375631
Nearest miRNA
hsa-mir-12123/Upstream/8795096; hsa-mir-10400/Downstream/2168916;
Nearest TSS
ENST00000518652/Upstream/227661; ENST00000517696/Downstream/580588;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/708317, chr8-CpG: 92/Downstream/720738
Nearby gene
LOC101929709
Upstream sequence
gcaaattcacacttaagatttgtgcatttcatttatataattttcacctcaaaagaaaaaactgtaaacaaacactgatctccaattaatgacacatatg
Downstream sequence
TTACAGATTAGGACGGGgctcagcctcaataattagtaaaatgtatattaaagcaattataaggtgtcactttaccactgaaattgattaaaaatagtaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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